MedSciNet

EASI: The Endovascular Acute Stroke Interventional Trial

EASI: The Endovascular Acute Stroke Interventional Trial

MedSciNet has implemented and helped launch the Endovascular Acute Stroke Interventional (EASI) trial.

EASI is a randomised, controlled multi-centre trial with the objective of comparing intra-arterial thrombectomy by endovascular means to standard medical treatment in patients with stroke due to occlusion of proximal large cerebral arteries.

Stroke constitutes the primary cause of acquired disability in adults and the second cause of dementia following Alzheimer disease. The burden of disease may be substantial since 25% of the victims of stroke are younger than 65 years.

The EASI trial aims to validate the use of intra-arterial thrombectomy during the acute phase of cerebral stroke in situations where the standard treatment of IV rtPA thrombolysis may not be optimal, as well as to determine whether a combined approach, standard treatment plus thrombectomy, is superior to standard treatment alone.

If the trial's primary hypothesis is validated, expected benefit of the study is a higher rate of autonomy for stroke patients with all the attendant consequences such as a reduction in hospital stays and a faster return to the activities of daily life.

The EASI trial is sponsored by Dr Jean Raymond and the CHUM-Notre Dame Hospital in Montreal, Canada.